周如鸿,男,舟山定海人,1984年毕业于舟山中学,后获美国哥伦比亚大学博士学位。现为IBM Watson 研究院软物质科学实验室主来自任, IBM蓝色基普因计划生命科学首席科学家,哥伦比亚大学化景学系兼职教授,美国科学促进会院士。
- 中文名称 周如鸿
- 国籍 中国
- 出生地 舟山定海
- 毕业院校 美国哥伦比亚大学
个怎啊风十丰过害人经历
在分子动力学模拟蛋白质结构,功能,以及动态过程、纳米尺度水运剧时旧的生物效应、以及纳米颗粒与生物分子的相互作用等研究领域成就显著。拥有或已申请14项美国专利。在权威学术刊物发表学术论文102篇,SCI引用3200余次。应邀在世界各地大学、研究机构和国所施棉式兴最际学术会议上做邀请报120余次,是期刊《Nanoscale》、《Current Physical Ch来自emistry》客座主编, 也是 《Current Bioinformatics》等6家国际期刊的编委。
代表论文
1. R. H. Zhou, X. H360百科uang, C. Margulius and B. J. Berne, Hydrophobic Collapse i明部抗界顾已弱n Multi-domain Protein Folding, Science, 305, 1605-160章史温酸行差9, 2004
2. P. Liu, X. Huang, R. H. Zhou and B. J. B关erne, Obs阿独烧胡价较ervation of a dewetting transition in the collapse of melittin tetramer, Nature, 437, 159-162, 2005
3. L. Cong, R. H. Zhou, Y品议市呢至周务饭英掌. C. Kuo, M. Cunniff, and F. Zhang纸尽期喜良半论, Comprehensive Interrogation of Natural T雷病ALE DNA Binding Modules and 核酒费策注帝夜思敌曾Transcriptional Repressor Domains, Nature Commun. 3, 968, 2012
4. Z. Xia, P. Clark, T. Huynh, P. Loher, Y. Zhao, H.W. Chen, P. 孔强Y. Ren, I. Rigoutsos, and R. H. Zhou, Molecular dynamics simulations of Ag买然停右状协均仍杂o silencing complexes reveal a large repertoire of admissible 'seed-less' targets, Scientif古化乐易次诗汽三阶述ic Reports, 迫顶货从及格拉质若2, 569, 20过条标板湖突适关体12
5. S. G. Kang, G. Q. Zhou, P. Yang, Y. Liu, B. Y. Sun, T. Huynh, H. Meng, L. Zhao, G. M. Xing, C. Y. Ch愿己歌还黄en, Y. L. Zhao, R似配诗经怀础零采采. H. Zhou, Molecular Mechanism of Pancreatic Tumor Metastases Inhibition by Metallofullerenol Gd@C82(OH)22: Implication for de novo Design of Nanomedicine, Proc. Natl. Acad. Sci., 109, in press, 2012
6. C. Ge, J. F. Du, L. Zhao, L. Wang, Y. Liu, D. H. Li, Y. Yang, R. H. Zhou, Y. L. Zhao, Z. F. Chai, C. Y. Chen, Binding of human serum proteins on single-wall carbon nanotubes reduces cytotoxicity, Proc. Natl. Acad. Sci, 108, 16968-16973, 2011 (featured article)
7. P. Das, J. A. King, and R. H. Zhou, Aggregation of ?D-Crystallin Associated with Human Cataracts via Domain Swapping at the C-terminal ?-strands, Proc. Natl. Acad. Sci. 108, 10514-10519, 2011 (featured article)
8. Y. Tu, P. Xiu, R. Wan, J. Hu, R. H. Zhou and H. Fang, Water-mediated signal multiplication with Y-shaped carbon nanotubes, Proc. Natl. Acad. Sci. 106, 18120-18124, 2009
9. L. Hua, R. H. Zhou, D. Thirumalai, B. J. Berne, Urea denaturation by stronger dispersion interactions with proteins than water implies a 2-stage unfolding, Proc. Natl. Acad. Sci., 105, 16928-16933, 2008
10. J. Li, X. Gong, H. Lu, D. Li, H. Fang and R. H. Zhou, Electrostatic Gating of a Nanometer Water Channel, Proc. Natl. Acad. Sci., 104, 3687-3692, 2007
11. R. H. Zhou, M. Eleftheriou, A. Royyuru, B. J. Berne, Destruction of long-range interactions by a single mutation in lysozyme, Proc. Natl. Acad. Sci., 104, 5824-5829, 2007
12. R. H. Zhou, Trp-cage: Folding Free Energy Landscape in Explicit Water, Proc. Natl. Acad. Sci., 100, 13280, -13285, 2003
13. R. H. Zhou and B. D. Silverman, Detecting native protein folds among large decoy sets with hydrophobic moments profiling, Proc. Paci. Symp. Biocomp. 2002, Eds. R. B. Altman, A. K. Dunker, L. Hunter, K. Lauderdale and T. E. Klein, p673-684, World Scientific, Singapore, 2002
14. R. H. Zhou, B. J. Berne and R. Germain, Free energy landscape of a beta-hairpin folding in explicit water, Proc. Natl. Acad. Sci. 98, 14931-14936, 2001
获奖情况
1. CAREER 队周高Award for Researchers "most lik来自ely to have the g360百科reatest scientific impact for IBM and the w引着orld" (at mo死室风试慢st five scientists chosen each year among eight IBM Labs worldwide), IBM Research, May, 2012
2. IBM Outstanding Innovation Award (OIA), IBM Corp重如运握劳缺呼讲促主. 2012
3. IBM Research Division Award, IBM Research (2012)
4. Will哥还区议体冷促标革孩充iam E. Schiesser Lecture, Lehigh University, April 2012
5. Elected to AAAS Fellow (A号采孔论准货酒素随merican Assoc食益位胞吸语测配大活iation of Advancement of Scien表罪主说需胞ce), 2011
6确论. Elected to APS Fellow (American Physical Society), 祖曲米处超定或常奏2011
7. Part of the IBM BlueGene Team who won 2009 National Me七孙雨重良味木施油dal on Innovation and Technology (presented by President Obama), 2009
8. IBM Invention Plateau Achievement Award, IBM Corporation (2009)
9. IBM Outstanding Technical Achievement Award (OT察度短措治AA, the highest technical 础封介方儿季四题事award of IBM), IBM Corp. (200雷厂也鲜临8)
10. IBM Outstanding Technical Achievement Award (OTAA), IBM Corp. (2005)
11. IBM Research Division Award, IBM Research (2005)
12. IBM Inventio顶长洲次原你n Plateau Achievement Award, IBM Corporation (2004)
13. IBM Invention Achievement Award, IBM Corporation (2002)
14. The Hammett Award for Best Ph.D. Graduates, Columb杂资封纸今程振满固杂子ia University (1997)
15. ACS Award on Comput守孩却二距慢一灯汉知ational Chem块宁双北啊换始老说罗istry (DEC Award), American Chemical Society (1995)
16. Faculty Fellowship, Columbia University (1994-1997)
17. Second Prize, Research in Science & Technology, China Ministry of Education (1993)
18. Best Paper Award for Outstanding Research, Zhejiang University (1993)
19. Award for Outstanding Research, Zhejiang University (1992)
知识产权
1. Bruce J. Berne and Ruhong Zhou, Fast methods for simulating biomolecular systems with long-range electrostatic interactions by molecular dynamics, US patent No. 5,915,230, Jun 22, 1999
2. Ruhong Zhou, Huafeng Xu, Ed Harder, and Bruce J. Berne, System and Method for Molecular Dynamics Simulation , US patent, No. 7,096,167 B2, August 22, 2006
3. Prasanna Athma, Ajay Royyuru, David Silverman and Ruhong Zhou, Method and apparatus for protein structure analysis, US Patent, No. 7,499,805, March 3, 2009
4. Ruhong Zhou, David Silverman, Ajay Royyuru, and Prasanna Athma, Hydrophobic Moment of Multi-domain Proteins, United States, US patent No. 7,877,214, Jan, 25, 2011
5. Ruhong Zhou, David Silverman, Ajay Royyuru, and Prasanna Athma, Hydrophobic Dipole Orientational Analysis for Multi-domain Protein Structures, US patent No. 8,010,332, Jan, 2012
6. Ruhong Zhou, and David Silverman, Method and Apparatus for Protein Structure Analysis, US patent filed (IBM Docket No. YOR920020224US1), Nov. 15, 2002
7. David Silverman, Ruhong Zhou and Ajay Royyuru, Hydrophobic Fourier Transform for Protein Structure Prediction Validation, US patent search (IBM Docket No. YOR820030692), September, 2003
8. Laxmi Parida and Ruhong Zhou, Pattern Discovery Analysis for Protein Folding Trajectories, US patent search (IBM Docket No. YOR820040227), April, 2004
9. Laxmi Parida and Ruhong Zhou, Clustering of Multidimentional Real-valued Data Using Signature Patterns, US patent (IBM Docket No. YOR820040321), May, 2004
10. Laxmi Parida and Ruhong Zhou, Visual Analysis of Pattern Landscape Animation, US patent (IBM Docket No. YOR920060233US1), March, 2006
11. Zhen Xia and Ruhong Zhou, Prediction of Influenza A Virus' Genetic Evolution with a Mutual Information Based Site Transition Network, IBM Docket No. YOR820090279, July 1, 2009
12. Payel Das and Ruhong Zhou, A biomimetic nano-pump for automatic separation of urea from water, DISCLOSURE NO. YOR820101155, November 12, 2010
13. Zhen Xia, Tien Hyunh, and Ruhong Zhou, Weighted mutual information method and automatic web server for influenza genetic variation prediction, DISCLOSURE NO. YOR820101065, October 18, 2010
14. James Kozloski, Cliff Pickover, Jacinta Wubben and Ruhong Zhou, System and Method for Competitive Binding of Sequence Annotations and Analysis Tools to Sequences in a Biological Data Repository, YOR820110975, October, 2011
15. Binquan Luan and Ruhong Zhou, Base-by-base Ratcheting DNA in a Y-shaped Carbon Nanotube, YOR820120589, May, 2012
16. Binquan Luan and Ruhong Zhou, Nanopore-Based Sensors for Detecting Nanotoxicity of a Carbon Nanotube to Proteins, YOR820120951, July, 2012