段金友，男，1974年11月生，安徽宿松人，博士，西北来自农林科技大学教授，博士生导师，入选陕西省'百人计划'、教育部'新世纪优秀人才支持计划'。
- 中文名称 段金友
- 出生地 安徽宿松
- 出生日期 1974年11月
- 毕业院校 中国科学院
- 学位/学历 博士
人物来自经历
1997年获得安徽师范大学学士学位，没2000年获得广西大学硕士学位，2003年获得中国科学院上海药物研究所博士学位。2003年11月至2005年360百科2月在美国约翰·霍普金斯大学从事糖脂功能博士后研究;2005年2月至2010年4月在美国哈佛大学医学院从事多糖免疫学博士后研究,并于2010年5月晋升为讲师;2010年7月聘为西北农林科大应用化学系教管犯破红阶可伟授、博士生导师。
学术兼职
船经用苦培经附都管第五届中国生物化学与分子生物所记程学会复合糖专业委员会委员、陕西省药学会理事、陕西省药端钱茶审置学会药物化学专委胞固块护径岩只会委员。
国际期刊"Journal of Pha转需穿称模兴料rmacy and Pharmacology"、"Therapeutics and Clinical Risk Management"等杂志的审稿人。
研究方向
多(寡)糖生物学:
1)天然多(寡)糖的功能机制:抗肿瘤、抗肥胖及肠道菌群调控等
2)基于多(寡)糖的药物构建及应用
开设课程
《有机化学》、《药来自物化学》、《糖生物学》、《酶学工程》
科研项目
省部级以上科研项目
国家自然科学基好烧研设态则曲既金面上项目(NS缺政介操歌甲导与FC31870799)
国360百科家自然科学基金面上项目(NSFC31570799)
国家自然科学基金面上项目(NSFC3127086赵绝线每季目振天红决需0)
教育部新世纪人才支持计划(NCET-13-0480)
上海中医药大学合作项目(K332021201).
学术论文
Synergistic clearance of intracellular 执九含玉每水pathogens by hyaluronan-streptomycin micelles encapsulated with rapamycin. Qiu Y, Lu C, Chen P, Sun F, Wang D, Wang Z, Hou C, Mu H, Duan J. Carb点介突件食ohydr Polym . 2019 Apr 15;210:364-371.
Protein-Bound β-glucan from Coriolus Versicolor has Potenti米张奏常异王菜联教待鸡al for Use Again刘亚八方过列呼声不st Obesity. Li X, Chen P, Zhang P, Chang Y, Cui M, Dua跳脱电哪连波南振医破火n J. Mol Nutr Foo升迅县验穿矛研连d Res . 2019 J的样气宗北志矛迫an 22:e1801231. doi: 10.1002/mnfr.201801231.
A photo-controlled h如跳yaluronan-based drug delivery nanosyst站亚站甲九孙径客越混em for cancer therapy. Sun F, Zhang P, Liu Y, Lu C, Qiu Y, Mu H, Duan J.Carbohydr Polym. 2019 Feb 15;206:309-318.
Light controllable chitosan micelles with ROS generation and essen八兴温设tial oil release for the treatm获乡ent of bacterial biofilm.Wang Z, Bai H, Lu C, Hou C, Qiu Y, Zhang P, Duan J, Mu H. C耐完说器情计曲真春心arbohydr Polym . 2019 Feb 1;205:533-539.
A些职友唱余顾ntidepressant and immunosupp价音ressive activ伤非色员ities of two polysaccharides from Poria cocos (Schw.) Wolf. Zhang W, Chen L, Li P, Zhao J, Duan J. Int J Biol Macromol . 2018 Dec;120(Pt B):1696-1704.
Sulfated modification and biological activities of polysaccharides derived from Zizyphus jujuba cv. Jinchangzao. Cai Y, Chen P, Wu C, Duan J, Bai H. Int J Biol Macromol . 2018 Dec;120(Pt A):1149-1155.
A hyaluronan-based nanosystem enables combined anti-inflammation of mTOR gene silencing and pharmacotherapy. Hou C, Bai H, Wang Z, Qiu Y, Kong LL, Sun F, Wang D, Yin H, Zhang X, Mu H, Duan J. Carbohydr Polym . 2018 Sep 1;195:339-348.
Inulin based glutathione-responsive delivery system for colon cancer treatment. Wang D, Sun F, Lu C, Chen P, Wang Z, Qiu Y, Mu H, Miao Z, Duan J. Int J Biol Macromol . 2018 May;111:1264-1272.
A novel photocleavable heparin derivative with light controllable anticoagulant activity. Sun F, Liu Y, Wang D, Wang Z, Mu H, Wang F, Ding K, Duan J. Carbohydr Polym . 2018 Mar 15;184:191-198.
Synthesis of hyaluronan-amikacin conjugate and its bactericidal activity against intracellular bacteria in vitro and in vivo. Wang Z, Qiu Y, Hou C, Wang D, Sun F, Li X, Wang F, Yi H, Mu H, Duan J. Carbohydr Polym . 2018 Feb 1;181:132-140.
Hyaluronic acid conjugation facilitates clearance of intracellular bacterial infections by streptomycin with neglectable nephrotoxicity. Qiu Y, Hou Y, Sun F, Chen P, Wang D, Mu H, Zhang X, Ding K, Duan J. Glycobiology . 2017 Sep 1;27(9):861-867.
Novel moisture-preserving derivatives of hyaluronan resistant to hyaluronidase and protective to UV light. Sun F, Niu H, Wang D, Wu Y, Mu H, Ma L, Duan J. Carbohydr Polym . 2017 Feb 10;157:1198-1204.
Synthesis, characterization and anticancer activity of tanshinone I grafted low molecular chitosan. Wang D, DanXu, Sun Y, Wu Y, Ma L, Duan J. Glycoconj J . 2017 Feb;34(1):3-12.
A tanshinone I derivative enhances the activities of antibiotics against Staphylococcus aureus invitro and invivo. Wang D, Lu C, Sun F, Cui M, Mu H, Duan J, Geng H. Res Microbiol . 2017 Jan;168(1):46-54.
Chitosan conjugation enables intracellular bacteria susceptible to aminoglycoside antibiotic.
Mu H, Niu H, Wang D, Sun F, Sun Y, Duan J. Glycobiology . 2016 Nov;26(11):1190-1197.
Preparation and sulfation of an α-glucan from Actinidia chinensis roots and their potential activities. Niu H, Song D, Sun Y, Zhang W, Mu H, Duan J. Int J Biol Macromol . 2016 Nov;92:981-987.
Autophagy promotes DNA-protein crosslink clearance. Mu H, Liu Q, Niu H, Wang D, Tang J, Duan J. Mutat Res Genet Toxicol Environ Mutagen . 2016 Feb;797:21-5.
Investigation of three lignin complexes with antioxidant and immunological capacities from Inonotus obliquus. Niu H, Song D, Mu H, Zhang W, Sun F, Duan J. Int J Biol Macromol . 2016 May;86:587-93.
Novel pH-sensitive polysialic acid based polymeric micelles for triggered intracellular release of hydrophobic drug. Zhang W, Dong D, Li P, Wang D, Mu H, Niu H, Duan J. Carbohydr Polym . 2016 Mar 30;139:75-81.
Structural characterization and biological activities of two α-glucans from radix paeoniae alba. Zhang W, Li P, Song D, Niu H, Shi S, Wang S, Duan J. Glycoconj J . 2016 Apr;33(2):147-57.
Potent Antibacterial Nanoparticles against Biofilm and Intracellular Bacteria. Mu H, Tang J, Liu Q, Sun C, Wang T, Duan J. Sci Rep. 2016 Jan 5;6:18877. doi: 10.1038/srep18877.
Characterization of polysaccharides with antioxidant and immunological activities from Rhizoma Acori Tatarinowii. Zhang W, Song D, Xu D, Wang T, Chen L, Duan J. Carbohydr Polym . 2015 Nov 20;133:154-62.
Unveiling the Mode of Action of Two Antibacterial Tanshinone Derivatives. Wang D, Zhang W, Wang T, Li N, Mu H, Zhang J, Duan J. Int J Mol Sci . 2015 Jul 31;16(8):17668-81.
Mechanistic insights into cellular immunity of chondroitin sulfate A and its zwitterionic N-deacetylated derivatives. Zhang W, Sun F, Niu H, Wang Q, Duan J. Carbohydr Polym . 2015 Jun 5;123:331-8.
Characterization of two water-soluble lignin metabolites with antiproliferative activities from Inonotus obliquus. Wang Q, Mu H, Zhang L, Dong D, Zhang W, Duan J. Int J Biol Macromol . 2015 Mar;74:507-14.
Chitosan improves anti-biofilm efficacy of gentamicin through facilitating antibiotic penetration. Mu H, Guo F, Niu H, Liu Q, Wang S, Duan J. Int J Mol Sci . 2014 Dec 3;15(12):22296-308.
Purification, antioxidant and immunological activities of polysaccharides from Actinidia Chinensis roots. Zhang L, Zhang W, Wang Q, Wang D, Dong D, Mu H, Ye XS, Duan J. Int J Biol Macromol . 2015 Jan;72:975-83.
Alteration in immune responses toward N-deacetylation of hyaluronic acid. Zhang W, Mu H, Dong D, Wang D, Zhang A, Duan J. Glycobiology . 2014 Dec;24(12):1334-42.
Extraction optimization, characterization and immunity activity of polysaccharides from Fructus Jujubae. Cui G, Zhang W, Wang Q, Zhang A, Mu H, Bai H, Duan J. Carbohydr Polym . 2014 Oct 13;111:245-55.
