周江宁

周江宁 男来自，教授，博士生导师，1956年10月4日生于南京 ， 1985年宁夏医学院硕士毕业。

1992-1996年荷兰阿姆斯特丹(AMSTERDAM)大学医学院毕业，获PhD医财学系博士学位。

1996-1998 荷烟茶办兰脑研究所博士后。1998年回国工作。

2001年入选中科院"百人计划"。

现任中科大神经生物学与生物物理学系主任，兼任中国神经科学会常务理事，中国药理学会抗衰老和痴呆专业委员会副主任委员。

2002年获安徽省科学技术进步奖(自然科学类)一等奖。

• 中文名称 周江宁
• 国籍 中国
• 民族 汉族
• 出生地 南京
• 出生日期 1956年10月4日

人物经历

　　来自周江宁 ，男, 1956年10月过充仍据血4日出生于江苏省南京市。现任中国科技大学生命科学院神经生物学与生物物理学系主任、神经生物学教授，博士生导师。中国神经科学学会常务理事、中国神经科学学会神经发育专业委员会主任委员行照沿列粉识温济树末。中国药理学会抗衰老和痴呆专业委员会副主任委员。

　　1985年宁夏医学院硕士毕业，1996年荷兰AMSTERDAM 大学医360百科学系博士毕业。1996年至1998年荷兰皇家科学院脑研究所博士后。1998年席它个蛋回国在安徽医科大学第一附属医院工作，曾任老年医学教授，副主任医师，副院长，安徽省老年病研究所所长，中科院知识创新工程重要方向项目首席科学家，中国科学神经科学会理事。2001年入选中国科学院"百人计划"。2002年建立了国内第一家"中国人脑库"。现为国家易谓宣酸知轻关973项目中期评估组专家成员。承担了国家重点基础研究发展规划项目(973)、国家高新技术领域规划项目(863)、国家国际合作重点项目、国家自然科学基金委项目等国家级项目九项，获资助经费近800万元。

研究获奖

　　主要从事神经精神系统疾病的发病机制与诊治基基补即却凯胜被础的研究。在以"Nature"为代表的SCI期刊发表论文40篇。Nature 论气酒头响做文被评为1995年世界100项重大科学发现之一。

周江宁

　　2000年获安徽省科技进步(自然科学类)一等奖。

　　2002年国际"性别鉴定研十想门距华请示系货迅学究和教育学会"研究论文奖;

　　国家"百千万"工程第一、第二层次人选;

　　客越国家级有突出贡献的中青年专家，教育部骨干教师，享受国务院政府特殊津贴。

研究方向

1. 脑的性分化和相关疾病
2. Alzheimer 病的发病机制和诊治基?
3. 抑郁症的发病机制和诊治基?

　　近五年承担国家科技计划项目情况:

代表论著

　　Zhou J-N., Hofman M. A., Gooren L. J. G and Swaab D. F. A sex difference in the human brain and its relation to transsexuality . Nature. V受宜创文资者未社ol.378,68-70 (1995).

　　Zhou J-N., Hofman M. A. and Swaab D. F.VIP neurons in the human SCN in relatio都跳福体友吃丰n to sex ,age and Alzheimer's disease. N美穿eurobiology of Aging. Vol.16,571-576(1995).

　　Zhou J-N., Hofman M. A. and Swaab D. F说什不印谓. No changes in the 最重先甚需争number of vasoactive intestinal polypep准析商急你压便尼tide(VIP)-expressing neurons in the suprachiasmatic nucleus of homosexual men; comparison with va节士玉状sopressin-expressing ne了供资这米汽九urons. Brain Research. Vol.672,285-288(19起空争血措极95).

　　Zhou J-N., Swaab D. F. Age-related c德hanges in neuropeptidergic neurons in the human hypothalamus. in Molecular Basis of Aging. ed by Macieira-Coelho A.CRC press,Boca R句失社aton, pp. 527-552(1995).

　　Zhou J-N.船会跑背, Hofman M. A. and Swaab D. F. Morphometric analysis of vasopressin and vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus, influence of microwa年李汉电派ve treatment. Brain Research. 742,334-338(1996).

　　Zhou J-N., Hofman M. A. and 球织没低夫承决晶材此Swaab D. F. Alteration in the human hypothalamus start in middle age but are more severe in Alzheimer's Disease. Neurobiology of Aging. 19, S309(1998).

　　Zhou J-N. and Swaab D. F. Activation and degeneration during aging, A morphometric study of the human hypothalamus. In Histology of the hypothalamic-pituitary axis. Microscopy Research and Techniques. 44, 36-48(1999).

　　Zhou J-N., Hu X-Y., Liu R-Y., Qin S. Ostrogen receptor containing neurons decrease in the hippocampus of Alzheimer patients. Neurobiology Aging. 21, s264(2000).

　　Zhou J-N., Riemersma R. F, Witte Hoogendijk. J. G., Swaab D. F. Alterations in Arginine Vasopressin Neurons in the Suprachiasmatic Nucleus in Depression. Arch Gen Psychlatry. VOL.58,July 2001;58,655-662(2001).

　　Zhou J-N., Liu R-Y., Van Heerikhuize J., Hofman M. A. and Swaab D. F. Alterations in the circadian rhythm of salivary melatonin begin during middle-age. J. Pineal Res. 34,11-16(2003).

　　周江宁 (2001) 衰老和老年性痴呆中昼夜节律调节系统的改变, 复旦神经生物学讲座, NO.255。

　　周江宁，刘荣玉.。 (2000) 老年性痴呆的非药物治疗 老年性痴呆的治疗和护理(盛树立主编), pp. 158-175， 科学技术文献出版社。

　　周江宁 (2002)雌激素与Alzheimer Disease.。神经科学进展(科学出版社)pp,315-318。

　　周江宁 (2001)前额叶皮质与下丘脑在抑郁症发病中的作用。安徽医科大学学报。Vol.36 No.4,247-250。

　　Liu R-Y, Zhou J-N., Hoogendijk W. J. G., Van Heerikhuize J., Kamphorst W, Unmehopa U. A., Hofman M. A., and Swaab D. F. Decreased vasopressin mRNA expression in the suprachiasmatic nucleus in Alzheimer's disease. J. Neuropath Exp Neurol. 59(4),314-322(2000).

　　Liu R-Y., Zhou J-N. Alteration of vasopressin mRNA expression in the suprachiasmatic nucleus of the patients with Alzheimer's disease. Neurobiology Aging. 21, s54(2000).

　　Liu R-Y, Zhou J-N, Van Heerikhuize J, Hofman M. A and Swaab D. F. Decreased melationin levels in postmortem cerebrospinal fluid in elation to aging, Alzheimer's disease and ApoE-ε4/4 genotype. J. Clin Endocr&Metab. 84,323-327(1999).

　　Liu R-Y, Zhou J-N, Kamphorst W, Hofman M.A, Swaab D.F The first appearance of neurofibrillary tangles and plaques in the temporal cortex of aged controls is accompanied by decreased cerebrospinal fluid melatonin levels. Neurobiology of aging. Vol.23, Iss1, pp,1397- (2002)

　　Liu R-Y, Zhou J-N (2001). Biological Rhytm disorder, In aging and Alzheimer's disease. Neuroendocrinologie des demences. Pp,11-30..

　　刘荣玉, 周江宁。糖皮质激素对人视交叉上核加压素表达的影响。中国药理学通报。16(3),286-289 (2000)。

　　刘荣玉, 周江宁。脑脊液松果体素昼夜和季节节律在衰老和老年痴呆中的改变。 中华老年医学杂志。19(4),258-261(2000)。

　　刘荣玉, 周江宁。人视交叉上核加压素基因表达的昼夜节律改变。安徽医科大学学报35(2),88-90(2000)。

　　Swaab D. F., Zhou J-N., Ehlhart T. and Hofman M. A. Development of vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus in relation to birth and sex. Development of Brain Research. Vol.79,249-259(1994).

　　Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Gender and sexual orientation-related differences in the human hypothalamus. in Sex differentiation clinical and biological aspect(ed.Hughes). Frontiers in Endocrinology 20, Cambridge, 135-152(1996).

　　Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Sexual differentiation of the human hypothalamus, differences according to sex, sexual orientation, and transsexuality in Sexual Orientation Toward Biological Understanding. (ed by Ellis L., Praeger, Westport) pp.129-150(1997).

　　Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Sexual differentiation of the human brain. Biomedical Reviews. 7, 17-32(1997).

　　Swaab D. F., Hofman M. A., Van Smeren E. J. W. and Zhou J-N. (1993). Development and aging of the biological clock. In De Biologische klok praktische toepassingen in klinjek en huisartspraktijk. (ed. Rietved W. J and Kerkhof G. A Leiden 1993) pp. 9-23.

　　Swaab D. F., Hofman M.A., Mirmiran M., Van Someren E. J. W., and Zhou J-N. The human suprachiasmatic mucleus (SCN) in a periodic environment. New functional aspect of the suprachiasmatic nucleus. pp. 232-336(1994).

　　Swaab D. F., Slob A. K., Houtsmuller E. J., Brand T. and Zhou J-N. Increased number of vasopressin neurons in the suprachiasmatic nucleus (SCN) of 'bisexual' adult male rats fllowing perinatal treatment with the aromataes blocker ATD. Dev. Brain Research. Vol.85,273-279(1995).

　　Swaab D.F, Fliers E, Hoogendijk W.J.G, Veltman D.J, Zhou J-N. Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression. Progress in brain research.Vol.126, pp,369-396(2001)

　　Swaab D.F., VanSomeren E.J.W., Zhou J-N, Hofman M.A. (1996) Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus. Hypothalamic integration of circadian rhythms. Vol.111, pp,349-368.

　　Hofman M.A., Zhou J-N, Swaab D.F. No evidence for a diurnal vasoactive intestinal polypeptide(VIP) rhythm in human suprachiasmatic nucleus. Brain Research. Vol.722,78-82(1996).

　　Hofman M.A., Zhou J-N, Swaab D.F. Suprachiasmatic nucleus of the human brain, An immunocytochemical and morphometric analysis. Anatomical Record. Vol.244,552-562(1996).

　　Hoogendijk W. J. G., Van Someren, E. J. W., Mirmiran M., Hofman M. A., Lucassen P. L., Zhou J-N and Swaab D. F. Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's disease. International Psychogeriatrics. Vol.8,245-252 (1996).

　　Kruijver F. P. M., Zhou J-N, Pool C. W., Hofman M. A., Gooren L. J. G., Swaab D. F. Male-to-female transsexuals have female neuron numbers in a limbic neurocleus. J Clin Endocr&Metab. 85,2034-2041 (2000).

　　Wang Q-S, Zhou J-N, Xu T-L, Li L-S A phospholipase C inhibitor, phenylmethylsulfonyl fluoride, ameliorates ischemic injury to brain mitochondria in rats. Acta Pharmacol Sin, Mar, 22(3),249-252 (2001).

　　Wang Q-S, Zhou J-N. Retrieval and encoding of epsodic memory in normal aging and patients with mild cognitive inpairment. Brain Research. 924,113-115(2002).

　　Wang Q-S, Tian L, Huang Y-L, Qin S, He L-Q, Zhou J-N. Olfactory identification and apolipoprotein Eε4 allele in mild cognitive impairment. Brain Research. 951,77-81(2002).

　　Wang Q-S, Qin S, Zhou J-N. Olfactory identification and apolipoprotein E epsilon-4 allele in mild cognitive impairment. Neurobiology of aging. Vol.23, Iss1, pp,635- (2002)

　　汪青松，许浩，秦松，赵卉，吴颖慧，黄永璐，周江宁。轻度认知损害患者情节记忆的编码和提取。中国神经科学杂志。Vol.18 No.1,451-463(2002)。

　　Hu X-Y, Zhang H-Y, Qin S, Xu H, Swaab D. F., Zhou J-N. (Increased p75NTR expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. Neurobiology of aging. Vol,23, Iss1, pp,997-.2002).

　　Hu X-Y, Zhou J-N, Swaab D.F Decreeased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphorylated tau in Alzheimer patients. Neurobiology of aging. Vol.23, Iss1, pp,1808- (2002).

　　Huang Y-L, Liu R-Y, Wang Q-S, Van Someren E.J.W., Xu H, Zhou J-N. Age-associated difference in circadian sleep-wake and rest-activity rhythms. Physiology&Behavior. 76, 597-603(2002).

　　黄永璐，汪青松，吴颖慧，周江宁。昼夜静息-活动、睡眠-觉醒节律的年龄相关性变化。安徽医科大学学报。Vol.37 No.1,44-46(2002)。

　　Xu H, Hu X-Y, Wu L, Zhou J-N.(2002) Neurotensin expressing neurons developed earlier than vasoactive intestinal polypeptide and vasopressin expressing neurons in the human suprachiasmatic nucleus. Neuroscience Letters.

　　许浩，胡祥友，秦松，周江宁。阿尔茨海默病脑海马凋亡神经元发生率增高。中国神经科学杂志。Vol.18 No.1,462-465(2002).

　　Wang K, Hoosain R, Li X-S, Zhou J-N, Wang C-Q, Fu X-M, Yue X-M. Impaired recognition of fear in a Chinese man with bilateral cingulated and unilateral amygdala damage. Cognitive neuropsychology. Vol.19,pp,641-652(2002).

　　Bao A-M, Zhou J-N, Liu R-Y, Wang Y-L, Cao Y-X, Chu X-H Circadian rhythm of free estrogen during menstrual cycle and its periodic regression analysis. Neurobiology of aging. Vol.23, Iss 1, pp,640-(2002)

　　陈贵海，周江宁。神经递质认识过程的哲学思考。医学与哲学。Vol.23 No.3,9-11(2002)。